Các hãng bay theo lịch trình

• Air Canada (Toronto-Pearson)
• American Airlines (Boston [seasonal], Miami, New York-JFK)
  • American Eagle (San Juan) [ngừng ngày 3 tháng 9]
• Aires (Barranquilla, Cartagena)
• Arkefly (Amsterdam, Willemstad)
• Aserca Airlines (Caracas, Santo Domingo)
• Avianca (Bogotá)
  • Avianca operated by SAM (Barranquilla, Bogotá, Medellin)
• Avior Airlines (Caracas, Maracaibo, Valencia)
• CanJet (Montreal)
• Caribair (Santo Domingo)
• Condor (Frankfurt)
• Continental Airlines (Houston-Intercontinental, New York-LaGuardia, Newark)
• Delta Air Lines (Atlanta, New York-JFK)

• Dutch Antilles Express (Kralendijk, Willemstad)
• First Choice Airways (London-Gatwick, Manchester)
• Insel Air (Willemstad)
• JetBlue Airways (Boston, New York-JFK)
• KLM (Amsterdam, Bonaire)
• Linea Aerea Aerocaribe (Las Piedras)
• Martinair (Amsterdam)
• Santa Barbara Airlines (Las Piedras, Maracaibo)
• Skyservice (Montreal, Toronto-Pearson)
• Spirit Airlines (Fort Lauderdale)
• Surinam Airways (Paramaribo/Zanderij, Port of Spain, Willemstad)
• Tiara Air (Kralendijk, Willemstad, Punto Fijo)
• Thomsonfly (Birmingham)
• United Airlines (Chicago-O'Hare, Washington-Dulles)
• US Airways (Boston, Charlotte, New York-La Guardia [seasonal], Philadelphia)
• Venezolana (Caracas, Maracaibo)
• Viva Air Dominicana (Santo Domingo)

Các hãng bay thuê bao

• Amerijet International (Miami, Santiago (DR), Santo Domingo)
• DHL Aero Expreso (International)
• Merlin Express (Puerto Rico)
• Ameriflight (San Juan)
• Líneas Aéreas Suramericanas (Bogotá)